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Biological targets
911 targets across the universe. Most are pursued by a single company — search, or start with the most-targeted below.
- CD19
- PD-1
- CD3
- PD-L1
- EGFR
- GLP-1 receptor
- BCMA
- HER2
- VEGF
- PSMA
- KRAS
- CD20
- RAS
- IL-4R
- CTLA-4
- DLL3
- dystrophin
- PRAME
- BTK
- VEGF-A
- TSLP
- IL-15
- IL-17A
- KRAS G12C
- MEK
- TL1A
- 4-1BB
- KRAS G12D
- APRIL
- GLP-1R
- TDP-43
- androgen receptor
- BRAF
- GLP-1
- FLT3
- FXN
- CD73
- FAP
- HTT
- 5-HT2A
- menin
- 5-HT7
- BAFF
- WT1
- IL-17F
- Nectin-4
- TGF-β
- CD122
- CFTR
- IL-2
- amyloid beta oligomers
- KIT
- 5-HT1A
- CD137
- Claudin 18.2
- MRGPRX2
- CD28
- PI3Kα
- CSF-1R
- JAK1
- MAPT
- NLRP3
- TMPRSS6
- DMPK
- FGFR2
- frataxin
- IL-4
- MECP2
- MC4R
- AXL
- VEGF receptors
- prostacyclin receptor
- telomerase
- TfR1
- D2
- D3
- mTOR
- ITK
- FcRn
- IL-13
- NMDA receptor
- alpha-synuclein
- CLDN18.2
- FGFR3
- IL-6
- TIGIT
- TTR
- B7-H3
- CD70
- GIP
- GIP receptor
- GIPR
- glucocorticoid receptor
- IL-23
- MAGE-A4
- PRMT5
- ROR1
- SCF
- TSHR
- WEE1
- AR
- C3d
- hepcidin
- IL-13Rα2
- IL-17
- KAT6
- KMT2A
- KRAS G12V
- mitochondrial dysfunction
- SOD1
- DHODH
- ENPP1
- GBA1
- HDAC
- IGF-1R
- IL-7Rα
- JAK2 V617F
- LPA1R
- MAPK
- MC1R
- melanocortin receptor
- Nrf2
- OX40
- PDE4
- PDE5
- PDGFR
- RAF
- STAT6
- tau
- TLR7
- TLR8
- VAV1
- 5T4
- BAG3
- CD47
- CD8+ T cells
- CDK2
- COL7A1
- DUX4
- dystrophin exon 45
- dystrophin exon 51
- dystrophin exon 53
- dystrophin gene
- estrogen receptor
- G6PC
- GM-CSF
- HBV
- huntingtin
- IL-17A/F
- IL-33
- IL-36R
- IRAK4
- ITGB6
- mitochondrial DNA
- NPM1
- NRAS
- OTC gene
- PAH
- PKP2
- PNPLA3
- PTK7
- RDH12
- SARS-CoV-2 spike protein
- SERPINA1
- SIRPα
- TNFα
- MET
- 5-HT2B
- H3 receptor
- PARP1
- Akt
- AMPA receptor
- HLA-A*02:01
- MER
- PI3K
- transthyretin
- TYRO3
- IP receptor
- p53 Y220C
- TARPγ8
- telomere
- AMPAR
- CETP
- D4
- LAT1
- RBP4
- activin A
- C1q
- CD1d
- DNRI
- ENPP3
- EpCAM
- farnesyl transferase
- GCase
- IL-15 receptor
- iNKT
- Kv7
- Kv7 potassium channel
- MT1
- MT2
- mTORC1
- PARG
- RET
- RHEB
- ActRIIA
- apoC-III
- APOC3
- AβOs
- CBL-B
- CCL24
- CD3 epsilon
- CDK9
- DR5
- ERK
- FcγRIIb
- glucan synthase
- glucocerebrosidase
- gp100
- GSK-3β
- HIF prolyl hydroxylase
- HIF-PH
- HJV
- IL-2 receptor complex
- IL-23 receptor
- IL-23R
- IL-2Rβ
- M4 muscarinic receptor
- nAChR α4β2
- NHE3
- NY-ESO-1
- p38α
- PKMYT1
- PKR
- pyruvate kinase
- pyruvate kinase R
- RASP
- ribosome
- Streptococcus pneumoniae capsular polysaccharides
- Survivin
- TACI
- TARP γ8
- Tau
- TGF-β ligands
- α4β7
- 5-HT2A receptor
- ACTH receptor
- activin B
- aldosterone synthase
- alpha-1 adrenergic receptor
- alpha-2 adrenergic receptor
- APOE2
- APOE4
- c-MET
- CAIX
- cardiac sarcomere
- CCR5
- CD105
- CD276
- CD40
- CD40L
- CD66
- CLDN6
- Complement Factor B
- CYP11B2
- DLL4
- endoglin
- Factor B
- Factor H
- FASN
- folate receptor alpha
- FRα
- GABA-aminotransferase
- GABA-AT
- GABAA receptor alpha-2
- GABAA receptor alpha-4
- GDF11
- GDF8
- glucagon receptor
- GlyT1
- GPRC5D
- H3 receptors
- IL-18BP
- IL-2 receptor
- inflammasome pathway
- influenza
- integrin receptors
- JAK3
- KIT D816V
- KIT exon 17
- KSR
- LAR family phosphatases
- leucyl-tRNA synthetase
- LeuRS
- M1 muscarinic receptor
- MAGEA8
- MASP-2
- NAD+
- NEK7
- NTCP
- Nurr1
- p-STAT3
- panKRAS
- PI3Ka
- PI3Kα RAS-binding domain
- PRLR
- prolactin receptor
- PTPσ
- regulatory T cells
- RORA
- SARS-CoV-2 Spike protein
- SCF248
- serotonin 5-HT2A receptor
- somatostatin receptor 2
- SRC
- SST2
- STAT3
- TLR-2
- TOP1
- YES1
- 5-HT2C
- 5HT-2
- 5HT-7
- 5HT7
- ActRIIB
- ALK5
- alpha-synuclein oligomers
- amylin receptor
- amyloid beta
- angiotensin II
- angiotensin II type 1 receptor
- APJ
- APLNR
- AQP1
- Bach1
- BAFF-R
- BBS10
- BEST1
- BLyS
- c-KIT
- c-Myc
- calcineurin
- calcitonin receptor
- calcium channel
- calpain
- CCR8
- CD5
- CD8
- CHK1
- CHK2
- cMET
- corticotropin-releasing factor receptor 1
- CRF1
- CTLA4-Ig
- CXCR4
- DLL-3
- DPP1
- endothelin type A receptor
- endothelin-1
- EP300
- EphA2
- FAK
- FGF23
- GABA-A receptor alpha-2
- GABA-A receptor alpha-4
- GITR
- GLP
- glucokinase
- GNA11
- GNAQ
- hAQP1
- hemojuvelin
- HGF
- HIF
- HIF-1α
- HSV-tk
- IGF-1
- IL-18
- IL-23p19
- IL-2R
- IL-36
- IL-4Ra
- IL-7
- IL23p19
- JAK2V617F
- kallikreins
- KAT7
- KRAS G12
- labile iron
- LAMB3
- LAT2
- leptin
- leucine-rich repeat kinase 2
- LPAR1
- LRRK2
- LSD1
- M1R
- MAGEA4/8
- MAPK pathway
- MC2R
- MEK 1
- MEK 2
- metallothionein
- MICA
- MICA/B
- MICB
- miR-124
- mKRAS
- myostatin
- NaPi2b
- Nav1.7
- nicotinic acetylcholine receptor
- NLRP3 inflammasome
- norepinephrine reuptake inhibitor
- NR2E3
- OX40L
- p38 MAP kinase alpha
- p38α MAP kinase
- p38α MAPK
- p53
- PD1
- PDE10A
- PDE7
- PDGFRα
- phosphorylated Tau
- PIK3CA
- PKC
- plasma kallikrein
- PlGF
- poly (ADP-ribose) glycohydrolase
- PRAME-A02
- protein kinase C
- PTH(1-34)
- RAS G12D
- RAS(ON)
- RAS(ON) G12C
- RAS(ON) G12D
- RXFP1
- S2R complex
- SARS-CoV-2
- SARS-CoV-2 spike protein RBD
- serine protease
- sigma-2 receptor
- SLC6A19
- SMN2
- somatostatin receptor
- SSTR2
- SSX2
- Stem Cell Factor 248
- TAS2Rs
- TGFβ
- thyroid hormone receptor beta
- Tissue Factor
- TMD1
- TNFR2
- TP53 Y220C
- TR-Beta
- transferrin receptor
- Tregs
- VEGF-B
- VEGF-C
- α-synuclein
- α4β2 nicotinic acetylcholine receptor
- α4β7 integrin
- α6β4 nAChR
- αvβ6 Integrin
- σ-2 receptor
- 3CL protease
- 5-HT1
- 5-HT1B
- 5-HT1B/1D
- 5-HT1B/1D Agonist
- 5-HT1D
- 5-HT2
- 5-HT6
- 5HT-2C
- 5HT4
- a-syn
- A2A receptor
- ADAR
- AIPL1
- alpha-1 antitrypsin
- alpha-7 nicotinic acetylcholine receptor
- alpha-galactosidase A
- alpha-lactalbumin
- AMHR2-ED
- AMPK
- AMY1R
- AMY2R
- AMY3R
- ANG-2
- ANG2
- ANGPTL3
- APE1/Ref-1
- apelin receptor
- APJ receptor
- Apo(a)
- APOL1
- ATP-sensitive potassium channel
- ATXN2
- auditory neuron progenitor cells
- AV node
- AβO
- B cells
- B4GALT1
- B7H3
- BCL11A
- BCL6
- BCR-ABL
- BCR::ABL
- BCR::ABL1
- BDCA2
- BDNF
- beta-glucuronidase
- beta-sarcoglycan
- BK virus
- BKV VP1
- BMP
- Brachyury
- BRD4
- c-Kit
- C1s
- C4A
- C5a peptidase
- calpain-2
- cancer stem cells
- cannabinoid receptors
- CAPN2
- carbonic anhydrase
- carbonic anhydrase IX
- cardiac troponin T
- CASQ2
- Cav1
- Caveolin-1
- CBP
- cccDNA
- CD-137
- CD117
- CD123
- CD134
- CD16
- CD18
- CD1a
- CD22
- CD23
- CD38
- CD39
- CD4+ T cells
- CD80
- CDH3
- CDK11
- CEA
- cereblon
- CIP2A
- CNGA3
- CNGB1
- CNGB3
- COL4A3
- COL4A4
- COL4A5
- Collagen IV
- complement factor B
- complement factor H
- connexin 43
- CoREST
- COX-2
- CPSF3
- CRF
- CRH
- CSF1
- CSPG
- CSPG-PTPσ
- CTR
- CUG repeat expansion
- Cx43
- Cyclophilin A
- CYP2D6
- cystathionine beta-synthase
- cytomegalovirus
- delta-like ligand 3
- Delta-like ligand 3
- dihydrofolate reductase
- dipeptidyl peptidase 1
- DMD exon 53
- DMPK mRNA
- DMPK RNA
- dopamine reuptake
- dopamine transporter
- duodenal mucosa
- dystrophin exon 44
- dystrophin exon 55
- dystrophin gene exon 45
- dystrophin gene exon 51
- dystrophin gene exon 53
- E342K
- EED
- EGFR exon 20
- EGFR exon 20 insertion
- EGFR L858R
- EGFR PACC
- EGFRvIII
- endoplasmic reticulum stress
- ER
- ErbB2
- ESR1
- exon 1 protein fragment
- exon 44
- exon 45
- exon 51
- exon 53
- exon 55
- factor B
- Factor IX
- FAP-α
- FcRH5
- FcεRI
- fetal hemoglobin
- FGFR1
- FGFR4
- fibroblast activation protein
- FMR1
- FMRP
- FSH-Receptor
- FSHR
- FUS
- G6Pase
- G6Pase-α
- GAA
- GABA
- GABA-A receptor
- GABA-A receptor α2,3 subtype
- GABAA receptor α2,3
- GABAA receptor α2,3 subtype
- GABAA α2/3
- GAD
- Gag
- Gag-A02
- gamma secretase
- GAN
- GCC
- GCG
- GCG receptor
- GCGR
- GFAP
- GICG
- GITR ligand
- GITRL
- GLA
- GLP-1RA
- GLP-2
- glucagon
- Glucagon
- GLUK2
- glycogen synthase 1
- glycolysis
- glypican 3
- gp120
- GP2
- GPC3
- GPR52
- GRIK2
- Group A carbohydrate
- GSPT1
- GUCY2D
- GYS1
- HBG1
- HBG1/2
- HBG2
- HBsAg
- HBV core protein
- HBV envelope antigen
- HBV RNA
- Hepatitis B antibodies
- hepatitis B surface antigen
- HER2/neu
- HERV-K envelope protein
- HIF-2a
- HIF-2α
- HIV
- HIV gag antigen
- HPK1
- HPV
- HPV E6
- HPV E7
- huntingtin gene
- hypoimmune iPSC
- ICL4
- ICP34.5
- IDUA
- IFN-β
- IFN-γ
- IFNα2b
- IgE
- IGHMBP2
- IKZF1
- IKZF1/3
- IKZF3
- IL-1
- IL-13Rα1
- IL-15R
- IL-17AA
- IL-17AF
- IL-18 binding protein
- IL-27
- IL-31
- IL-36 receptor
- IL-36α
- IL-36α/γ
- IL-36γ
- IL-6/JAK1
- IL-6R
- IL-7R alpha
- IL13R alpha1
- IL4R alpha1
- INHBE
- integrated HBV DNA
- integrin alpha v beta 6
- integrin β6
- interferon alpha-2b
- IpaB
- IpaH
- IRF5
- ITGB2
- K Env
- K-ATP channels
- KAT6A
- KCC2
- KLK2
- KLK5
- KLKB1
- KRAS G13C
- KRAS Q61H
- Kv7.2/3
- L-type calcium channel
- LAMP2
- LAMP2B
- LCA5
- light chain fibrils
- lipoprotein(a)
- Lp(a)
- LPA1
- lysine acetyltransferase 6
- lysine acetyltransferase 7
- M1
- M1 receptor
- M1/M4 agonist
- M1/M4 Muscarinic Agonist
- M4
- MAT2A
- MBNL1
- MC5R
- MCHR1
- MCR
- Measles Fusion (F) protein
- MEK1
- MEK1/2
- MEK2
- melanin-concentrating hormone receptor type 1
- Menin
- menin-KMT2A
- MERTK
- mHTT
- microdystrophin
- mineralocorticoid receptor
- mitochondrial KATP channel
- MMP7
- MT1-MMP
- MTAP
- MUC1
- N-protein
- NAGLU
- Nav1.1
- NaV1.1
- Nav1.2
- Nav1.6
- NBD1
- nectin-4
- NECTIN4
- neuraminidase
- NF-KB
- NGF
- nicotinic acetylcholine receptors
- NKG2A
- NMDA
- NMNAT1
- NOD2
- norepinephrine reuptake
- norepinephrine transporter
- Notch pathway
- Nrf1
- NRf2
- NS3/4A protease
- NS5A
- oligodendrocyte progenitor cells
- OPA1
- orexin 2 receptor
- orexin-2 receptor
- OTC
- OX2R
- P-Cadherin
- p38α kinase
- PDGF
- PDGF receptor
- phenylalanine hydroxylase
- photoreceptors
- PI3K/mTOR
- PI3Kα H1047R
- PIWIL1
- PKD1
- PKD2
- PKK
- PKM2
- PLK4
- polyclonal antibodies
- polycystin-1
- polycystin-2
- polyglutamine-expanded androgen receptor
- polyQ-AR
- potassium and hyperpolarization-activated cyclic nucleotide-gated voltage gated ion channels
- PPAR-delta
- PPI x PD1-A02
- PRC2
- pre-pro-insulin
- prekallikrein
- Protein Tyrosine Kinase 7
- PSA
- PTH1R
- PVRIG
- R408W
- R83C
- RAGE
- RAS Q61H
- RAS(ON) G12V
- Rb-E2F pathway
- RBM20
- RBM39
- RelA
- RetGC
- retinal pigmented epithelial cells
- rhNAGLU
- RHO
- ROR2
- RPE65
- RPGR
- RSV
- RSV L-protein
- RSV N-protein
- RSV neutralizing antibodies
- RYR2
- S. pneumoniae antibodies
- SARS-CoV-2 nucleocapsid protein
- SARS-CoV-2 spike protein receptor binding domain
- sclerostin
- SCN1A
- serotonin receptor
- serotonin receptors
- serotonin transporter
- SETDB1
- sGC
- SGSH
- sigma-1
- SIRT6
- SLC10A1
- SN38
- SNP3
- soluble guanylate cyclase
- somatostatin receptor subtype 2
- SpyAD
- STEAP1
- streptolysin O
- SUR2B
- SYK
- T-lymphocytes
- TAAR1
- TAS2R
- tau mRNA
- TF
- TGFβR1
- thymocytes
- TIE-2
- tissue factor
- TLR2
- TNFa
- TNFR1
- TNFRSF9
- TNNI3
- TNNT2
- topoisomerase II
- TP53
- transferrin receptor 1
- TRBV6
- troponin C
- troponin I
- TXK
- TYK2
- UBE3A
- UBE3A-ATS
- UPF1
- URAT1
- USP1
- V2 receptor
- VE-PTP
- VEGFR
- VirG
- VISTA
- VLA-4
- voltage-gated sodium channels
- Wilms Tumor 1
- Wnt/β-catenin
- WRN
- α7-nAChR
- β2-adrenergic receptor
No targets match.