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Biological targets
422 targets across the universe. Most are pursued by a single company — search, or start with the most-targeted below.
- CD19
- PD-1
- GLP-1 receptor
- CD3
- HER2
- PD-L1
- BCMA
- VEGF
- APRIL
- EGFR
- FLT3
- FXN
- 5-HT2A
- WT1
- CD122
- KIT
- TSLP
- androgen receptor
- IL-4R
- STAT6
- dystrophin
- frataxin
- 5-HT7
- FcRn
- BAFF
- CD20
- PRAME
- TL1A
- KRAS G12C
- menin
- IKZF1
- IKZF3
- IL-6
- KRAS G12D
- MRGPRX2
- 5-HT1A
- ITK
- MAGE-A4
- CTLA-4
- GLP-1R
- IL-13Rα2
- mitochondrial dysfunction
- CSF-1R
- GBA1
- IL-2
- IRAK4
- JAK1
- KRAS
- MAPT
- PSMA
- tau
- BAG3
- CD33
- CD73
- DMPK
- DUX4
- GM-CSF
- HTT
- IL-36R
- ITGB6
- Nrf2
- PKP2
- SERPINA1
- MC4R
- BTK
- 5-HT2B
- TfR1
- GSK-3β
- p53 Y220C
- telomerase
- telomere
- D2
- D3
- D4
- IL-15 receptor
- Nectin-4
- RASP
- C1q
- FASN
- GCase
- IL-13
- MEK
- MT1
- MT2
- CD70
- ERK
- farnesyl transferase
- glucocerebrosidase
- HIF prolyl hydroxylase
- HIF-PH
- IL-17A
- IL-17F
- IL-23
- IL-2Rβ
- Kv7
- Kv7 potassium channel
- MASP-2
- nAChR α4β2
- NY-ESO-1
- p38α
- PI3Kα RAS-binding domain
- PRLR
- PRMT5
- serotonin 5-HT2A receptor
- somatostatin receptor 2
- Survivin
- TACI
- TTR
- α4β7
- 5-HT2A receptor
- ACTH receptor
- APOE2
- APOE4
- B7-H3
- BAFF-R
- C3d
- CD8
- CDK9
- DHODH
- Factor H
- GABA-aminotransferase
- GABA-AT
- GIP receptor
- glucagon receptor
- inflammasome pathway
- influenza
- integrin receptors
- JAK3
- KIT D816V
- KIT exon 17
- KMT2A
- KRAS G12V
- KSR
- MAGEA8
- NAD+
- NEK7
- NMDA receptor
- panKRAS
- prolactin receptor
- SARS-CoV-2 Spike protein
- SST2
- VEGF-A
- 5-HT2C
- amylin receptor
- amyloid beta oligomers
- angiotensin II
- angiotensin II type 1 receptor
- AV node
- AβOs
- beta-sarcoglycan
- BLyS
- c-KIT
- calcitonin receptor
- calcium channel
- CCR5
- CD276
- CD5
- CD80
- CFTR
- CHK1
- CHK2
- Claudin 18.2
- dihydrofolate reductase
- endothelin type A receptor
- endothelin-1
- ErbB2
- FGF23
- GIPR
- GLP-1
- glucokinase
- HBsAg
- HIF
- HPK1
- IGF-1R
- IL-15
- IL-18
- IL-23p19
- IL-31
- IL-4
- IL-4Ra
- IL-6/JAK1
- KCC2
- L-type calcium channel
- labile iron
- LAR family phosphatases
- LRRK2
- MAPK
- MC2R
- MEK 1
- MEK 2
- melanocortin receptor
- NLRP3
- NLRP3 inflammasome
- NR2E3
- OX40L
- p38α MAP kinase
- p38α MAPK
- p53
- PDE5
- PDE7
- PDGF
- PDGF receptor
- PDGFR
- PKMYT1
- polyQ-AR
- PTPσ
- RORA
- S2R complex
- SSX2
- TDP-43
- thyroid hormone receptor beta
- Tissue Factor
- TP53 Y220C
- TR-Beta
- VAV1
- VEGF receptors
- WEE1
- α-synuclein
- α4β7 integrin
- σ-2 receptor
- 3CL protease
- 5-HT1
- 5-HT2
- 5-HT6
- 5HT4
- A2A receptor
- ADAR
- alpha-7 nicotinic acetylcholine receptor
- alpha-galactosidase A
- alpha-sarcoglycan
- ANGPTL3
- AR
- ATP7B
- AXL
- B cells
- Bach1
- BCL11A
- BCL6
- BDCA2
- beta-glucuronidase
- BK virus
- BKV VP1
- Brachyury
- BRD4
- C1s
- C4A
- calpain-2
- cannabinoid receptors
- CAPN2
- carbonic anhydrase
- cardiac troponin T
- CASQ2
- CBD
- CBL-B
- CCR8
- CD117
- CD123
- CD137
- CD18
- CD47
- CDH3
- CDK11
- CEA
- connexin 43
- CoREST
- CRF
- CRH
- Cx43
- Cyclophilin A
- cystathionine beta-synthase
- cytomegalovirus
- DLL3
- DMD exon 53
- DMPK RNA
- dopamine transporter
- DPD
- duodenal mucosa
- dysferlin
- dystrophin exon 44
- dystrophin exon 45
- dystrophin exon 51
- dystrophin exon 53
- dystrophin exon 55
- dystrophin gene exon 45
- dystrophin gene exon 51
- dystrophin gene exon 53
- E342K
- endoplasmic reticulum stress
- EpCAM
- ER
- ESR1
- estrogen receptor
- exon 44
- exon 45
- exon 51
- exon 53
- exon 55
- Factor IX
- FAP-α
- fetal hemoglobin
- FGFR2
- FGFR3
- FMR1
- FMRP
- G6Pase-α
- G6PC
- GAA
- GABAA α2/3
- gamma-sarcoglycan
- GIP
- GLA
- GLUK2
- GP2
- GRIK2
- GSPT1
- HBG1
- HBG1/2
- HBG2
- HBS1L
- HBV
- HBV core protein
- HDAC
- hepatitis B surface antigen
- HER2/neu
- HIF-2a
- HIF-2α
- HPV
- HPV E6
- HPV E7
- huntingtin
- huntingtin gene
- hydroxychloroquine
- IFNα2b
- IGF-1
- IGHMBP2
- IKZF1/3
- IL-1
- IL-13Rα1
- IL-27
- IL-36α
- IL-36α/γ
- IL-36γ
- INHBE
- integrin alpha v beta 6
- interferon alpha-2b
- IRF5
- ITGB2
- KLKB1
- Kv7.2/3
- LAMP2
- LAMP2B
- light chain fibrils
- LPA1R
- MC1R
- MECP2
- MER
- MET
- mHTT
- microdystrophin
- MUC1
- N-protein
- NAGLU
- Nav1.2
- Nav1.6
- Nav1.7
- NOD2
- norepinephrine transporter
- Nrf1
- OTC gene
- P-Cadherin
- p38 MAP kinase alpha
- PAH
- PDE4
- PI3Kα
- PNPLA3
- polyglutamine-expanded androgen receptor
- potassium and hyperpolarization-activated cyclic nucleotide-gated voltage gated ion channels
- PPAR-delta
- Protein Tyrosine Kinase 7
- PSA
- PTK7
- R408W
- R83C
- RAGE
- RAS
- Rb-E2F pathway
- RBM20
- rhNAGLU
- RSV L-protein
- RSV N-protein
- RYR2
- SCF
- sclerostin
- serotonin receptor
- serotonin transporter
- sGC
- SGSH
- SN38
- SNP3
- SOD1
- soluble guanylate cyclase
- SSTR2
- tau mRNA
- TF
- TGF-β
- THR-β
- TIE-2
- TIGIT
- TLR2
- TLR7
- TLR8
- TNFa
- TNNI3
- TNNT2
- troponin I
- TXK
- TYRO3
- UBE3A antisense
- URAT1
- VE-PTP
- VEGFR
- β2-adrenergic receptor
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