vTv Therapeutics
Market cap $84.4M 4.0M shares (vendor count, Nov 7, 2026) × $21.03 close Nov 6, 2026 · share count from the market-data vendor, not the SEC cover page
Most recent annual filing: 2026-03-15
- CATT1 Ph3 toplinemid-2027CATT1 Ph3 topline, mid-2027, major
- Cadisegliatin T2D Ph2 start2H 2027Cadisegliatin T2D Ph2 start, 2H 2027, routine
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (9 active programs)
TTP273
TTP-RA
mavodelpar
HPP593 · REN001- Undisclosed indication
HPP971
- Undisclosed indication
HPP737
- Undisclosed indication
HPPD
HPP8668Discontinued (1)
- azeliragon — Alzheimer's Disease · Phase 3 STEADFAST program terminated (NCT02080364 / NCT02916056 TERMINATED; NCT03980730 Phase 2 TERMINATED); the 10-Q carries azeliragon only under 'Other projects' with no development activity
Capital (as filed)
- Cash
- $77.2M cash and cash equivalents · Sep 30, 2026 (10-Q)
- Operating cash flow
- −$10.2M quarter Jun 30, 2026 → Sep 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $77.2M cash, runway anticipated CATT1 topline data readout per the update of Nov 5, 2026 — the company's own words as read there, not the filed figure
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (7)
- 2026-10-09 UPDATE: vTv Therapeutics (VTVT) - Millennium Doubles Down 🔒 Paid
- 2026-10-06 UPDATE: vTv Therapeutics (VTVT) - The Clock Is Set 🔒 Paid
- 2026-08-07 UPDATE: vTv Therapeutics (VTVT) - The Gun They Didn't Fire 🔒 Paid
- 2026-05-14 UPDATE: vTv Therapeutics (VTVT) – The ATM Refresh on Earnings Day 🔒 Paid
- 2026-03-29 UPDATE: vTv Therapeutics (VTVT) - Smart Money Buys the Delay
- 2026-03-14 UPDATE: vTv Therapeutics (VTVT) – A Biotech Delay Hits Phase 3 🔒 Paid
- 2026-02-04 vTv Therapeutics (VTVT): Scientific Deep Dive for Cadisegliatin and Pipeline Products 🔒 Paid
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (7 calls)
Every verdict Biotech Distilled has published on vTv Therapeutics, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-02-04 Speculative buy speculative vTv Therapeutics (VTVT): Scientific Deep Dive for Cadisegliatin and Pipeline Products Hepatoselective chemistry addresses historical GKA toxicity failures, the company is fully funded through the binary Phase 3 readout, and the hypoglycemia-sparing benefit is the real commercial value driver.
- 2026-03-14 Speculative buy speculative UPDATE: vTv Therapeutics (VTVT) – A Biotech Delay Hits Phase 3 The thesis is delayed not broken; enrollment slip pushes topline to Q1-Q2 2027 but the balance sheet comfortably covers the extended runway and the hepatoselective chemistry conviction is unchanged.
- 2026-03-29 Speculative buy speculative UPDATE: vTv Therapeutics (VTVT) - Smart Money Buys the Delay Millennium Management's 5% passive stake validates the runway math and confirms institutional confidence in the hepatoselective chemistry thesis despite the enrollment delay.
- 2026-05-14 Hold UPDATE: vTv Therapeutics (VTVT) – The ATM Refresh on Earnings Day The ATM refresh to $47.5M on earnings day introduces a real dilution overhang and the burn rate came in 35% above model, softening the 'no dilution gap' claim and making the entry point unattractive until the overhang clears.
- 2026-08-07 Speculative buy speculative UPDATE: vTv Therapeutics (VTVT) - The Gun They Didn't Fire Zero ATM shares sold in two consecutive quarters demonstrates management restraint, enrollment remains on track for Q3 2026, and the dilution feared in May has not materialized, justifying re-upgrade for those who can wait through the Q1-Q2 2027 readout.
- 2026-10-06 Speculative buy speculative UPDATE: vTv Therapeutics (VTVT) - The Clock Is Set CATT1 fully enrolled at 166 patients (above the 150-patient design), retiring enrollment risk and pinning topline to mid-2027, while the price has drifted back to May levels offering an improved risk/reward for patient investors.
- 2026-10-09 Speculative buy speculative UPDATE: vTv Therapeutics (VTVT) - Millennium Doubles Down Millennium grew its passive stake ~73% to 8.7% during the dead-money drift and before enrollment news was public, reinforcing institutional conviction in the mid-2027 binary readout at current ~$30 prices.
- Long call · opened Feb 4, 2026 at $36.41 · -42.2% vs XBI +21.5% (Nov 6, 2026)
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (3 quotes from 3 filings)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“A total of 166 patients were randomized in the study and the Company expects to report topline results from the CATT1 study in mid-2027.”
matched to CATT1 (Phase 3) · topline data · read as mid-2027
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““Completing enrollment in the Phase 3 CATT1 trial is a significant milestone for vTv, and we look forward to reporting topline results in mid 2027,” said Paul Sekhri, Chairman, President and Chief Executive Officer of vTv Therapeutics.”
matched to CATT1 (Phase 3) · topline data · read as mid 2027
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“We expect to initiate a Phase 2 study in patients with T1D using hybrid closed loop insulin infusion systems in late 2026.”
matched to CATT1 (Phase 3) · topline data · read as late 2026 / matched to Cadisegliatin (T1D) · topline data · read as late 2026
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Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (25)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from May 7, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Nov 5, 2026ReleasevTv Therapeutics Reports Third Quarter 2026 Financial Results and Provides Corporate UpdateSummary on the 8-K
- Nov 5, 20268-KCurrent report: results of operations · EX-99.1vTv's Q3 print arrives with VTVT down ~28% from early October — the stock's slide predates tonight's release, and three of the most watched variables (ATM, cash runway, timeline) are mostly holding, though a CFO 10b5-1 plan and a quiet G42 timeline slip deserve attention.
- Nov 5, 202610-QQuarterly reportSummary on the 8-K
- Oct 27, 2026ReleasevTv Therapeutics Announces First Participant Randomized in Phase 2a Pilot Study Evaluating Cadisegliatin in Individuals with Type 1 Diabetes (T1D) Using Hybrid Closed-Loop (HCL) Insulin Delivery SysteThe Hybrid CATT1 clock just started — vTv randomized its first patient into the Phase 2a study of cadisegliatin in closed-loop pump users, tackling the payer objection I flagged as the drug's biggest commercial hurdle. Here's what the trial design tells us, and what it doesn't.
- Oct 10, 2026ReleasevTv Therapeutics Announces Oral Presentation at Breakthrough T1D Clinical and Research Congress 2026
- Oct 7, 2026ReleasevTv Therapeutics Announces FDA Orphan Drug Designation for HPPD in Sickle Cell DiseaseThe FDA just handed vTv's Nrf2/Bach1 modulator an Orphan Drug Designation in sickle cell disease — a pipeline asset the prior writeup called a "science project" just became a partnering card with real regulatory currency.BD extracted 1 program update from this document → VTVT pipeline
- Oct 6, 2026ReleasevTv Therapeutics to Host Virtual KOL Event on Hypoglycemia in Type 1 Diabetes and the Cadisegliatin Phase 3 Program on October 20, 2026
- Oct 6, 20268-KCurrent report: charter / bylaws / fiscal year
- Oct 5, 2026ReleasevTv Therapeutics Announces Completion of Enrollment in Phase 3 CATT1 Study of Cadisegliatin in Type 1 Diabetes (T1D)→ BD updatevTv just confirmed CATT1 enrollment is complete — 166 patients randomized, on the Q3 2026 schedule promised three quarters running. The bet-the-company readout is now locked in for mid-2027, and the clock is officially ticking.
- Sep 2, 2026ReleasevTv Therapeutics to Participate in September Investor Conferences
- Aug 6, 2026ReleasevTv Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update
- Aug 6, 20268-KCurrent report: results of operations · EX-99.1
- Aug 6, 202610-QQuarterly report
- Jun 29, 20268-KCurrent report: shareholder vote
- Jun 10, 2026DEFA14AProxy soliciting material
- May 13, 2026ReleasevTv Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update
- May 13, 20268-KCurrent report: results of operations · EX-99.1
- May 13, 20268-KCurrent report: other events
- May 13, 2026424B2Prospectus supplement
- May 13, 202610-QQuarterly report
- May 7, 2026ReleasevTv Therapeutics to Participate in Upcoming May Investor Conferences
- Apr 28, 2026DEF 14AProxy statement
- Mar 10, 20268-KCurrent report: Reg FD disclosure · EX-99.1
- Mar 10, 20268-KCurrent report: results of operations · EX-99.1
- Mar 10, 202610-KAnnual report
5 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Oct 8, 2026SCHEDULE 13G/A13G amendment→ BD updateMillennium Management quietly grew its VTVT stake from 5.0% to 8.7% — adding 144,244 shares through the ATM scare, the enrollment delay, and the dead-money drift — and the market hasn't priced it yet.
- Jul 29, 2026SCHEDULE 13G/A13G amendment
- May 13, 2026S-8Employee plan registration
- Apr 16, 2026SCHEDULE 13G/A13G amendment
- Mar 27, 2026SCHEDULE 13GPassive >5% holder (13G)