Tenax Therapeutics
Market cap $77.0M 45.5M shares (10-Q, Oct 31, 2026) × $1.69 close Nov 6, 2026
Most recent annual filing: 2026-03-10
- TNX-103 enrollment doneend of 2027TNX-103 enrollment done, end of 2027, notable
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (2 active programs)
levosimendan
TNX-102Discontinued (1)
- imatinib — Pulmonary Arterial Hypertension · deprioritized the planned Phase 3 clinical trial of imatinib; no significant imatinib development activities ongoing
Capital (as filed)
- Cash
- $114M cash and cash equivalents · Sep 30, 2026 (10-Q)
- Operating cash flow
- −$12.5M quarter Jun 30, 2026 → Sep 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $114M cash, runway through fiscal 2028 per the update of Nov 5, 2026 — the company's own words as read there, not the filed figure
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (8)
- 2026-11-06 UPDATE: Tenax Therapeutics (TENX) - Grading Its Own Homework
- 2026-09-09 UPDATE: Tenax Therapeutics (TENX) - Fidelity Left, ADAR1 Arrived 🔒 Paid
- 2026-08-31 UPDATE: Tenax Therapeutics (TENX) - Munich Answered the Question I Asked 🔒 Paid
- 2026-08-11 UPDATE: Tenax Therapeutics (TENX) - The Coin Landed Tails
- 2026-07-31 UPDATE: Tenax Therapeutics (TENX) - The 2030 Cliff Just Moved to 2035 🔒 Paid
- 2026-07-08 UPDATE: Tenax Therapeutics (TENX) - Fidelity Shows Up at 14.9% 🔒 Paid
- 2026-07-02 Tenax Therapeutics (TENX) — Scientific Deep Dive for TNX-103 and Pipeline Products 🔒 Paid
- 2026-07-02 UPDATE: Tenax Therapeutics (TENX) - The Clock Just Got a Date on It 🔒 Paid
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (8 calls)
Every verdict Biotech Distilled has published on Tenax Therapeutics, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-07-02 Watch Tenax Therapeutics (TENX) — Scientific Deep Dive for TNX-103 and Pipeline Products The LEVEL binary is a coin-flip at a fully-diluted valuation already embedding meaningful success, making it watchable but not ownable on fundamentals.
- 2026-07-02 Watch UPDATE: Tenax Therapeutics (TENX) - The Clock Just Got a Date on It Catalyst timing tightened to August and ESC late-breaker slot confirmed, but science, capital structure, and valuation asymmetry are unchanged — still a coin-flip binary not worth new capital at this price.
- 2026-07-08 Watch UPDATE: Tenax Therapeutics (TENX) - Fidelity Shows Up at 14.9% Fidelity's 14.9% stake alongside T. Rowe's 17.2% is a modestly constructive ownership signal, but valuation asymmetry has narrowed further and the science is unchanged — still a coin-flip binary.
- 2026-07-31 Watch UPDATE: Tenax Therapeutics (TENX) - The 2030 Cliff Just Moved to 2035 The Orion license deadline extension to 2035 removes the timeline trap bear-case pillar, but clinical risk is unchanged and the fully-diluted valuation still embeds meaningful success — remains a coin-flip binary.
- 2026-08-11 Avoid UPDATE: Tenax Therapeutics (TENX) - The Coin Landed Tails LEVEL failed its primary endpoint decisively (3.5m, p=0.63), the financing lever is gone with warrants underwater, and the remaining case is a subgroup hypothesis that does not yet warrant capital.
- 2026-08-31 Watch UPDATE: Tenax Therapeutics (TENX) - Munich Answered the Question I Asked The ESC dataset added KCCQ corroboration, multiplicity-adjusted echo data, and a regression-to-the-mean rebuttal to the low-walk subgroup, making the hypothesis materially stronger — but the pivotal still failed and FDA has not spoken, so only a speculative watch is warranted.
- 2026-09-09 Watch UPDATE: Tenax Therapeutics (TENX) - Fidelity Left, ADAR1 Arrived Fidelity exited and specialist financing capital ADAR1 arrived at 14.0%, signaling a probable dilutive raise ahead; science and FDA timing are unchanged — lottery-ticket sizing near cash value.
- 2026-11-06 Watch UPDATE: Tenax Therapeutics (TENX) - Grading Its Own Homework LEVEL-2 enrichment criteria derived post hoc from the failed trial inflate the reported 34m effect; enrollment is paused, FDA has not yet spoken, and the stock trades below cash — lottery-ticket sizing pending Q1 2027 FDA readout.
- Avoid call · opened Aug 11, 2026 at $1.62 · closed Sep 1, 2026 (downgraded to WATCH from avoid) at $1.80 · +11.1% vs XBI +3.4%
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (2 quotes from 2 filings)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“We completed randomization in the LEVEL trial at the end of the first quarter of 2026 and expect to report topline data in August 2026.”
matched to TNX-103 · topline data · read as August 2026 / matched to TNX-103 · enrollment complete · read as August 2026
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“We completed randomization in the LEVEL trial at the end of the first quarter of 2026 and expect to report topline data in August 2026.”
matched to TNX-103 · topline data · read as August 2026 / matched to TNX-103 · enrollment complete · read as August 2026
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Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (26)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from Jul 31, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Nov 5, 2026ReleaseTenax Therapeutics Reports Third Quarter 2026 Financial Results and Provides Corporate Update→ BD updateSummary on the 8-K
- Nov 5, 20268-KCurrent report: results of operations · EX-99.1→ BD updateThe Q3 10-Q revealed a tighter LEVEL-2 enrichment design (+34 m in qualifying patients, 95% CI 15–53), confirmed the Type C meeting is granted, disclosed a securities class-action lawsuit, and showed the August 2024 warrant tranche expired worthless — four developments that collectively update the post-LEVEL bear and watch-list picture.
- Nov 5, 202610-QQuarterly report→ BD updateSummary on the 8-K
- Oct 8, 20268-KCurrent report: other events · EX-99.1BD extracted 1 program update from this document → TENX pipeline
- Sep 9, 20268-KCurrent report: Reg FD disclosure · EX-99.1BD extracted 1 program update from this document → TENX pipeline
- Sep 1, 2026ReleaseTenax Therapeutics to Participate in the 2026 Cantor Global Healthcare Conference
- Aug 29, 2026ReleaseTenax Therapeutics Announces Presentation of Phase 3 LEVEL Results in Late-Breaking Scientific Sessions at ESC Congress 2026→ BD updateThe full LEVEL dataset landed at ESC Munich, and the subgroup story got sharper — but the primary endpoint miss stands, and a prespecified split in a failed trial is still a hypothesis, not a win.
- Aug 10, 2026ReleaseTenax Therapeutics Announces Topline Results from Phase 3 LEVEL Clinical Trial of TNX-103 in Patients with PH-HFpEF
- Aug 10, 20268-KCurrent report: other events · EX-99.1
- Jul 31, 2026SCHEDULE 13D/A13D amendment
- Jul 31, 2026ReleaseTenax Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update
- Jul 31, 20268-KCurrent report: results of operations · EX-99.1
- Jul 31, 202610-QQuarterly report
- Jul 2, 20268-KCurrent report: other events · EX-99.1BD extracted 1 program update from this document → TENX pipeline
- Jun 30, 20268-KCurrent report: material agreement
- Jun 29, 20268-KCurrent report: officer / director change, other events
- Jun 4, 20268-KCurrent report: shareholder vote
- May 12, 20268-KCurrent report: results of operations · EX-99.1
- May 12, 202610-QQuarterly report
- Apr 22, 2026DEFA14AProxy soliciting material
- Apr 22, 2026DEF 14AProxy statement
- Apr 22, 20268-KCurrent report: officer / director change, other events · EX-99.1
- Mar 24, 2026S-3Shelf registration
- Mar 10, 2026SCHEDULE 13DActivist / >5% holder (13D)
- Mar 10, 20268-KCurrent report: results of operations · EX-99.1 PRESS RELEASE
- Mar 10, 202610-KAnnual report
43 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Oct 27, 2026SCHEDULE 13G/A13G amendment
- Oct 15, 2026SCHEDULE 13G/A13G amendment
- Oct 13, 2026SCHEDULE 13G/A13G amendment
- Oct 9, 2026SCHEDULE 13G/A13G amendment
- Sep 11, 2026SCHEDULE 13G/A13G amendment
- Sep 8, 2026SCHEDULE 13G/A13G amendment→ BD updateSummary on the SCHEDULE 13G
- Sep 8, 2026SCHEDULE 13GPassive >5% holder (13G)→ BD updateFidelity quietly cut its TENX stake from 14.9% to 1.4% as of August 31 — the same day as the ESC presentation — while ADAR1 Capital Management emerged as a new 14.0% holder. The crossover anchor I called "conviction capital" voted with its feet; a new name stepped in.
- Aug 27, 2026SCHEDULE 13GPassive >5% holder (13G)
- Aug 27, 2026SCHEDULE 13GPassive >5% holder (13G)
- Aug 18, 2026SCHEDULE 13GPassive >5% holder (13G)
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 12, 2026SCHEDULE 13G/A13G amendment
- Jul 30, 2026SCHEDULE 13GPassive >5% holder (13G)
- Jul 17, 2026SCHEDULE 13G/A13G amendment
- Jul 8, 2026SCHEDULE 13GPassive >5% holder (13G)
- Jun 5, 2026SCHEDULE 13G/A13G amendment
- May 20, 2026SCHEDULE 13GPassive >5% holder (13G)
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 12, 2026S-8Employee plan registration
- May 8, 2026SCHEDULE 13G/A13G amendment
- May 7, 2026SCHEDULE 13G/A13G amendment
- May 7, 2026SCHEDULE 13G/A13G amendment
- May 4, 2026SCHEDULE 13G/A13G amendment
- Apr 22, 2026ARSAnnual report to shareholders
- Apr 8, 2026SCHEDULE 13G/A13G amendment
- Apr 7, 2026SCHEDULE 13G/A13G amendment
- Apr 1, 2026EFFECTRegistration effective
- Mar 31, 2026CORRESPCORRESP
- Mar 27, 2026UPLOADUPLOAD
- Mar 9, 2026SCHEDULE 13GPassive >5% holder (13G)