Kiora Pharmaceuticals
Market cap $6.4M 4.4M shares (10-Q, Aug 5, 2026) × $1.44 close Nov 6, 2026
Most recent annual filing: 2026-01-15
- Tranche A-1 warrants corporate updateJan 2027Tranche A-1 warrants corporate update, Jan 2027, routine
- KIO-401 corporate update2027KIO-401 corporate update, 2027, routine
- KIO-301 topline3Q 2027KIO-301 topline, 3Q 2027, major
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (4 active programs)
KIO-101
mitucapistat
KIO-401- Central Retinal Artery Occlusion
- Non-Arteritic Anterior Ischemic Optic Neuropathy
Technology platforms
Ion Channel Modulator
Novel ion channel modulator platform with membrane-calming effects; primary focus on retinal disease (reducing pathological retinal hyperactivity); exploratory expansion into neurological disorders including epilepsy where neuronal hyperexcitability is implicated
Discontinued (2)
- KIO-104 — Diabetic Macular Edema · strategic deprioritization to focus on KIO-401
- KIO-104 — Posterior Non-Infectious Uveitis · strategic deprioritization to focus on KIO-401
Capital (as filed)
- Cash
- $7.1M cash and cash equivalents · Jun 30, 2026 (10-Q)
- Short-term investments
- $9.8M Jun 30, 2026
- Operating cash flow
- −$1.9M quarter Mar 31, 2026 → Jun 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $16.8M cash, runway late 2028 per the update of Oct 29, 2026 — the company's own words as read there, not the filed figure
Offering documents (2)
- 2026-05-28 424B3 · Resale (selling stockholders)
- 2026-05-18 S-3 · Shelf registration
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (7)
- 2026-10-30 UPDATE: Kiora Pharmaceuticals (KPRX) - The Pivot to Eye Stroke 🔒 Paid
- 2026-09-09 UPDATE: Kiora Pharmaceuticals (KPRX) - They Hired the Phase 3 Guy 🔒 Paid
- 2026-08-19 UPDATE: Kiora Pharmaceuticals (KPRX) - The Last Map Pin Gets Filled 🔒 Paid
- 2026-08-08 UPDATE: Kiora Pharmaceuticals (KPRX) - The Runway Stretches, and a Catalyst Quietly Moves Up 🔒 Paid
- 2026-04-27 UPDATE: KIORA PHARMACEUTICALS INC (KPRX) - Perceptive Shows Up, Nature Medicine Prints, and the Warrant Structure Tells You the Plan 🔒 Paid
- 2026-03-28 UPDATE: Kiora Pharmaceuticals (KPRX) - A 12-Month Delay, a $4.6M Impairment, and the Value of Deep-Pocketed Partners 🔒 Paid
- 2026-03-09 Kiora Pharmaceuticals (KPRX): Scientific Deep Dive for KIO-301 and Pipeline Products 🔒 Paid
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (7 calls)
Every verdict Biotech Distilled has published on Kiora Pharmaceuticals, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-03-09 Watch Kiora Pharmaceuticals (KPRX): Scientific Deep Dive for KIO-301 and Pipeline Products Elegant chemistry with a funded partner removing dilution risk, but N=6 open-label data makes efficacy a coin toss until double-masked ABACUS-2 reads out.
- 2026-03-28 Watch UPDATE: Kiora Pharmaceuticals (KPRX) - A 12-Month Delay, a $4.6M Impairment, and the Value of Deep-Pocketed Partners A 12-month delay to Q3 2027 ABACUS-2 data ties up capital longer, but the TOI-funded runway into late 2027 and no forced dilution keep the watch thesis intact.
- 2026-04-27 Speculative buy speculative UPDATE: KIORA PHARMACEUTICALS INC (KPRX) - Perceptive Shows Up, Nature Medicine Prints, and the Warrant Structure Tells You the Plan Perceptive's at-market anchor investment, Nature Medicine peer-review validation, runway extension to late 2027 without toxic dilution, and a contractual mandate for a strategic transaction shift the calculus enough to start a position on dips below $2.00.
- 2026-08-08 Speculative buy speculative UPDATE: Kiora Pharmaceuticals (KPRX) - The Runway Stretches, and a Catalyst Quietly Moves Up Runway extended to late 2028, ABACUS-2 high-dose cohort underway, and KIO-104 KLARITY readout pulled into late 2026 shorten the wait and improve the setup without changing the core binary risk.
- 2026-08-19 Speculative buy speculative UPDATE: Kiora Pharmaceuticals (KPRX) - The Last Map Pin Gets Filled South Korea partnership completes the global commercial map and a coordinated single global Phase 3 is now on record, incrementally strengthening the M&A and partnering thesis while ABACUS-2 remains the central binary.
- 2026-09-09 Speculative buy speculative UPDATE: Kiora Pharmaceuticals (KPRX) - They Hired the Phase 3 Guy Hiring a 12-global-Phase-3 veteran as EVP of Global Clinical Development closes the CDO succession gap and signals intent to architect the coordinated global Phase 3, modestly reducing execution risk.
- 2026-10-30 Watch UPDATE: Kiora Pharmaceuticals (KPRX) - The Pivot to Eye Stroke In-licensing a self-funded Phase 3 asset (KIO-401) built on a missed primary endpoint, killing the wholly-owned KIO-104 hidden gem, and announcing an unpriced raise destroys the outsourced-cost-risk pillar that underpinned the speculative buy thesis.
- Long call · opened Apr 27, 2026 at $2.32 · closed Oct 30, 2026 (downgraded to WATCH from long) at $1.56 · -32.8% vs XBI +17.2%
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Filings & releases (23)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from May 8, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Oct 29, 2026ReleaseKiora Pharmaceuticals In-Licenses Late-Stage, Oral Neuroprotective Calpain Inhibitor for Central Retinal Artery Occlusion (CRAO) with Planned Expansion into NAION; Asset Completed Phase 3 Clinical Tri→ BD updateSummary on the 8-K
- Oct 29, 20268-KCurrent report: material agreement, Reg FD disclosure · EX-99.1→ BD updateKiora dropped a bombshell this morning: it in-licensed KIO-401, an oral calpain inhibitor with completed Japanese Phase 3 data, while simultaneously killing KIO-104 — the stock's nearest-term catalyst. The market took the news badly, sending KPRX down ~25% on the day.BD extracted 5 program updates from this document → KPRX pipeline
- Sep 8, 2026ReleaseKiora Pharmaceuticals Appoints Keith J. Lane as Executive Vice President of Global Clinical Development and Regulatory Affairs→ BD updateSummary on the 8-K
- Sep 8, 20268-KCurrent report: officer / director change, Reg FD disclosure · EX-99.1→ BD updateThe CDO succession watch item flagged in April is now resolved: Kiora hired Keith Lane, a 20-year ophthalmic drug development veteran with 12 global Phase 3 studies under his belt, as EVP of Clinical Development — closing the leadership gap ahead of the global KIO-301 Phase 3.
- Aug 19, 2026ReleaseKiora Pharmaceuticals Licenses South Korean Ophthalmic Development and Commercialization Rights for KIO-301 to Chong Kun Dang Pharmaceutical Corporation
- Aug 19, 20268-KCurrent report: material agreement, Reg FD disclosure · EX-99.1
- Aug 7, 2026ReleaseKiora Pharmaceuticals Reports Second Quarter 2026 Financial Results and Provides Corporate Update
- Aug 7, 20268-KCurrent report: results of operations · EX-99.1
- Aug 7, 202610-QQuarterly report
- Jul 2, 2026ReleaseKiora Pharmaceuticals to Participate in Piper Sandler Virtual Ophthalmology Symposium
- Jun 18, 2026ReleaseKiora Pharmaceuticals Reports its Ion Channel Modulator, KIO-300, Suppressed Seizure Activity in Preclinical Epilepsy Model
- Jun 18, 20268-KCurrent report: Reg FD disclosure · EX-99.1
- Jun 11, 20268-KCurrent report: officer / director change, shareholder vote
- May 28, 2026424B3Prospectus (resale / update)
- May 18, 2026S-3Shelf registration
- May 8, 2026ReleaseKiora Pharmaceuticals Reports First Quarter 2026 Financial Results and Provides Corporate Update
- May 8, 20268-KCurrent report: results of operations · EX-99.1
- May 8, 202610-QQuarterly report
- Apr 30, 2026DEF 14AProxy statement
- Apr 7, 20268-KCurrent report: material agreement, unregistered sale of equity, Reg FD disclosure · EX-99.1
- Apr 2, 20268-KCurrent report: officer / director change, Reg FD disclosure · EX-99.1
- Mar 25, 20268-KCurrent report: results of operations · EX-99.1
- Mar 25, 202610-KAnnual report
13 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Sep 17, 2026SCHEDULE 13GPassive >5% holder (13G)
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 10, 2026SCHEDULE 13GPassive >5% holder (13G)
- May 22, 2026EFFECTRegistration effective
- May 20, 2026UPLOADUPLOAD
- May 20, 2026CORRESPCORRESP
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13GPassive >5% holder (13G)
- May 1, 2026ARSAnnual report to shareholders
- Apr 21, 2026DForm D (exempt offering)
- Mar 25, 2026S-8Employee plan registration