PBGENE-HBV
Gene Therapy Target: cccDNA, integrated HBV DNA
Precision Biosciences
Most recent annual filing: 2026-03-12
Pipeline (4 active programs)
PBGENE-DMD
Gene Therapy Target: dystrophin gene
PBGENE-3243
Gene Therapy Target: mitochondrial DNA
- Mitochondrial Disease
ECUR-506
Gene Therapy Target: OTC gene
Technology platforms
ARCUS
ARCUS is a single-component genome editing platform based on engineered meganucleases. It enables gene insertion, elimination, and excision via staggered DNA cuts. Compatible with AAV and LNP delivery; small size allows inclusion of insertion DNA template in a single AAV. Applicable to genetic diseases, infectious diseases, and immunotherapy.
Discontinued (1)
- azercabtagene zapreleucel — undisclosed
Biotech Distilled coverage (1)
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