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X4 Pharmaceuticals
Market cap $325M 102.1M shares (10-Q, Nov 2, 2026) × $3.18 close Nov 6, 2026
Most recent annual filing: 2026-03-17
Q3Q4Q1 ’27Q2Q3Q4Q1 ’28Q2
- 4WARD CN enrollment done4Q 20264WARD CN enrollment done, 4Q 2026, routine
- K2 loan agreement corporate update4Q 2026K2 loan agreement corporate update, 4Q 2026, routine
- X4 Pharmaceuticals corporate updateNov 2026X4 Pharmaceuticals corporate update, Nov 2026, routine
- mavorixafor XOLREMDI corporate updateNov 2026mavorixafor XOLREMDI corporate update, Nov 2026, routine
- X4 Pharmaceuticals corporate updateNov 30, 2026X4 Pharmaceuticals corporate update, Nov 30, 2026, routine
- mavorixafor XOLREMDI) commercial launch2027mavorixafor XOLREMDI) commercial launch, 2027, routine
- 4WARD CN topline1Q 20284WARD CN topline, 1Q 2028, thesis-defining
- mavorixafor XOLREMDI filingApr 26, 2028mavorixafor XOLREMDI filing, Apr 26, 2028, notable
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a
six-month window. Deeper blue means more of the thesis rides on the event; it is not a
view on the stock.
Pipeline (2 active programs)
XOLREMDI
mavorixafor · X4P-001 Capital (as filed)
- Cash
- $186M cash and cash equivalents · Sep 30, 2026 (10-Q)
- Operating cash flow
- −$20.2M quarter Jun 30, 2026 → Sep 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $188M cash, runway Q1 2029 per the update of Nov 4, 2026 — the company's own words as read there, not the filed figure
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (2)
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (2 calls)
Every verdict Biotech Distilled has published on X4 Pharmaceuticals, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-10-09 Watch X4 Pharmaceuticals (XFOR) - Scientific Deep Dive for Mavorixafor (XOLREMDI) and Pipeline Products Mavorixafor is a real approved drug with a validated mechanism and credible specialist investors, but the CN infection thesis has no randomized evidence, the trial has been resized twice with a shifting power claim, and cash reaches the readout but not the launch.
- 2026-11-05 Watch UPDATE: X4 Pharmaceuticals (XFOR) - The Covenant Lands K2 covenant terms failed the 'benign' gate, locking up ~$60M from October 2027 and making a pre-topline equity raise likely, while valuation has drifted higher without any improvement in the probability of success; enrollment close remains the key remaining gate.
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (3 quotes from 3 filings)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“The trial is designed to enroll approximately 25 patients, with the first participant expected to be enrolled in the first quarter of 2027 and top-line data expected in the first quarter of 2028.”
matched to 4WARD (mavorixafor, CN) · topline data · read as first quarter of 2027
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“Full enrollment (N=126) expected by end of Q4 2026”
matched to 4WARD (mavorixafor, CN) · topline data · read as Q4 2026
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“Full enrollment expected in Q4 2026”
matched to 4WARD (mavorixafor, CN) · topline data · read as Q4 2026
Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (19)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first.
Releases captured from Oct 8, 2026;
filings from March 2026.
Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Nov 4, 2026ReleaseX4 Pharmaceuticals Reports Third Quarter 2026 Financial Results and Provides Corporate Update→ BD updateSummary on the 10-Q
- Nov 4, 202610-QQuarterly report→ BD updateThe Q3 10-Q finally discloses the K2 covenant structure — a 75%-of-debt cash lock starting Oct 1, 2027 that compresses usable runway ahead of the H1 2028 4WARD readout — while 4STEPS emerges as a new clinical program and WHIM sales tick up for the first time in three quarters.
- Nov 3, 2026ReleaseX4 Pharmaceuticals to Participate in Guggenheim, Stifel, and Jefferies Conferences in November 2026
- Oct 29, 2026ReleaseX4 Pharmaceuticals Highlights Clinical Progress and Market Opportunity for Mavorixafor in Primary Chronic Neutropenia During Virtual Investor Day
- Oct 29, 20268-KCurrent report: other events · EX-99.1
- Oct 9, 2026ReleaseX4 Pharmaceuticals to Host Virtual Investor Day on Thursday, October 29, 2026, Featuring Key Opinion Leaders
- Oct 8, 2026ReleaseX4 Pharmaceuticals Secures Up to $150 Million Senior Debt Facility with K2 HealthVenturesvia aggregator
- Oct 8, 20268-KCurrent report: material agreement, agreement terminated, debt / obligation · EX-99.1
- Sep 9, 20268-KCurrent report: other events · EX-99.1
- Sep 8, 20268-KCurrent report: other events · EX-99.1
- Aug 6, 202610-QQuarterly report
- Jul 1, 20268-KCurrent report: officer / director change, Reg FD disclosure · EX-99.1
- May 13, 20268-K/ACurrent report (amended): officer / director change, shareholder vote
- May 12, 20268-KCurrent report: officer / director change, shareholder vote
- May 6, 2026S-3Shelf registration
- May 6, 202610-QQuarterly report
- Mar 20, 2026DEFA14AProxy soliciting material
- Mar 20, 2026DEF 14AProxy statement
- Mar 17, 202610-KAnnual report
12 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Oct 7, 2026SCHEDULE 13G/A13G amendment
- Sep 21, 2026SCHEDULE 13GPassive >5% holder (13G)
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Jul 30, 2026SCHEDULE 13GPassive >5% holder (13G)
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 14, 2026EFFECTRegistration effective
- May 12, 2026CORRESPCORRESP
- May 11, 2026UPLOADUPLOAD
- Mar 20, 2026ARSAnnual report to shareholders
- Mar 18, 2026S-8Employee plan registration
- Mar 6, 2026SCHEDULE 13G/A13G amendment