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Sutro Biopharma

Market cap $160M 16.6M shares (10-Q, Aug 7, 2026) × $9.62 close Nov 6, 2026

Most recent annual filing: 2026-03-23

Catalyst timeline

2 trackedQuarter catalyst calendar →
  1. STRO-006 IND filing2026STRO-006 IND filing, 2026, notable
  2. STRO-227 IND filing2H 2026STRO-227 IND filing, 2H 2026, notable

Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.

Pipeline (4 active programs)

Technology platforms

XpressCF · Vaxcyte

Cell-free protein synthesis platform enabling rapid production of complex biologics including ADCs, iADCs, bispecific ADCs, and dpADCs for oncology; also licensed to Vaxcyte for infectious disease vaccine development

XpressCF+ · Astellas

Site-specific conjugation platform enabling non-natural amino acid incorporation and precise dual-payload conjugation for homogeneous ADCs, iADCs, bispecific ADCs, and dpADCs in oncology

XpressCF

Cell-free protein synthesis platform (XpressCF® and XpressCF+®) used to generate site-specific and novel-format antibody-drug conjugates for oncology programs including STRO-004, STRO-006, and STRO-227

Discontinued (2)

Capital (as filed)

Cash
$54.3M cash and cash equivalents · Jun 30, 2026 (10-Q)
Short-term investments
$110M Jun 30, 2026
Operating cash flow
−$38.3M quarter Mar 31, 2026 → Jun 30, 2026, year-to-date difference (10-Q)
As stated in coverage
$164M cash, runway at least Q2 2028 per the update of Aug 12, 2026 — the company's own words as read there, not the filed figure

Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.

Biotech Distilled coverage (2)

Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.

Verdict history (2 calls)

Every verdict Biotech Distilled has published on Sutro Biopharma, oldest first — the full history, never a selection. How calls are scored: the track record.

  1. Speculative buy speculative Sutro Biopharma (STRO) - Scientific Deep Dive for Lead and Pipeline Products High-risk, high-reward platform turnaround with a make-or-break mid-2026 STRO-004 Phase 1 binary catalyst; balance sheet stabilized post-offering but CMO tech transfer and clinical translation remain key risks.
  2. Buy core UPDATE: Sutro Biopharma (STRO) - The Binary Event Landed STRO-004 Phase 1 data confirmed the safety hypothesis in humans — 12% epistaxis vs. ~70% with Tivdak, 98% DAR8 retention, and CMO execution validated — upgrading from speculative to core buy despite efficacy remaining unquantified and next readout a year away.

Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.

Timing, in the company's words (6 quotes from 3 filings)

Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.

Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.

Filings & releases (17)

SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from Aug 12, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →

14 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)