Nuvectis Pharma
Market cap $719M 34.4M shares (10-Q, Oct 30, 2026) × $20.91 close Nov 6, 2026
Most recent annual filing: 2026-02-11
- NXP200 U.S. IND filing4Q 2026NXP200 U.S. IND filing, 4Q 2026, material
- NXP900 Ph1 readout1H 2027NXP900 Ph1 readout, 1H 2027, material
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (9 active programs)
ciprocopan
NXP100 · HSK39297NXP200
HSK42360Discontinued (1)
- NXP800 — Ovarian Cancer · following the completion of a Phase 1b clinical study, we decided to cease clinical development of NXP800
Capital (as filed)
- Cash
- $141M cash and cash equivalents · Sep 30, 2026 (10-Q)
- Operating cash flow
- −$25.3M quarter Jun 30, 2026 → Sep 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $141M cash, runway 2H 2029 per the update of Nov 4, 2026 — the company's own words as read there, not the filed figure
Offering documents (2)
- 2026-08-21 S-3 · Shelf registration up to $200M aggregate
- 2026-06-30 424B5 · Priced offering 5.00M shares · at $20.00 · $100M gross · 29.9% below the prior close ($28.53, Jun 29, 2026)
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (10)
- 2026-11-05 UPDATE: Nuvectis Pharma (NVCT) - The ATM Found One Big Buyer, and the Canary Slipped Again 🔒 Paid
- 2026-10-27 UPDATE: Nuvectis Pharma (NVCT) - The Lottery Ticket Shows Its Numbers 🔒 Paid
- 2026-08-22 UPDATE: Nuvectis Pharma (NVCT) - A $200M Shelf and a Jefferies ATM, Seven Weeks After “Runway Into 1H 2029” 🔒 Paid
- 2026-08-07 UPDATE: Nuvectis Pharma (NVCT) - The Empty Register Just Got Its First Name 🔒 Paid
- 2026-08-05 UPDATE: Nuvectis Pharma (NVCT) - The Summer Binary Just Quietly Became a Winter Footnote 🔒 Paid
- 2026-07-24 UPDATE: Nuvectis Pharma (NVCT) - The Portfolio Anchor Just Cleared a Regulator 🔒 Paid
- 2026-06-30 UPDATE: Nuvectis Pharma (NVCT) - The Financing Print I Was Waiting For 🔒 Paid
- 2026-06-30 UPDATE: Nuvectis Pharma (NVCT) - The Deal Priced Below My Yellow Flag 🔒 Paid
- 2026-06-23 UPDATE: Nuvectis Pharma (NVCT) - The One-Asset Company Just Bought Two More 🔒 Paid
- 2026-06-02 Nuvectis Pharma (NVCT) — Scientific Deep Dive for NXP900 🔒 Paid
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (10 calls)
Every verdict Biotech Distilled has published on Nuvectis Pharma, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-06-02 Watch Nuvectis Pharma (NVCT) — Scientific Deep Dive for NXP900 Differentiated SRC/YES1 conformation-locking mechanism with real PD receipts, but no human efficacy data, a single patent family expiring 2036, and a binary summer readout racing a dilutive raise make this a wait-for-data situation.
- 2026-06-23 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - The One-Asset Company Just Bought Two More The Haisco licensing deal converts a one-asset Phase 1a binary into a diversified three-program story with late-stage Factor B and BRAF assets, but the deal is conditional on a raise that hasn't priced, warranting an engaged but cautious speculative position.
- 2026-06-30 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - The Deal Priced Below My Yellow Flag The $20 print with a retail-tilted six-co-manager syndicate at a 30% discount-to-last is a yellow-flag outcome, but the Haisco financing condition is retired at 2x the floor and the thesis itself is intact; the institutional sponsorship question now rests on upcoming 13G filings.
- 2026-06-30 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - The Financing Print I Was Waiting For The Cantor-led marketed offering resolves the financing-condition overhang on the Haisco deal at a radically better price than modeled, retiring the binary financing risk, though the final discount and allocation quality remain unknowns.
- 2026-07-24 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - The Portfolio Anchor Just Cleared a Regulator Ciprocopan's NMPA approval as the world's first once-daily oral Factor B inhibitor validates the mechanism and the head-to-head Soliris data, but the institutional register remains empty and the ex-China regulatory framing is still needed to re-rate the stock.
- 2026-08-05 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - The Summer Binary Just Quietly Became a Winter Footnote The thesis has rotated from a one-asset SRC/YES1 binary to a late-stage complement company fully funded into 1H 2029 with a U.S. regulatory clock starting 4Q2026, though NXP900's readout slipped from summer to year-end and narrowed to combinations only.
- 2026-08-07 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - The Empty Register Just Got Its First Name Soleus Capital's 5.1% 13G filing partially redeems the retail-syndicate concern from the June 30 print, confirming at least one healthcare-dedicated specialist underwrote the thesis, though one holder is a foothold not a crowded register.
- 2026-08-22 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - A $200M Shelf and a Jefferies ATM, Seven Weeks After "Runway Into 1H 2029" The new $200M shelf and $75M Jefferies ATM represent opportunistic financial flexibility at 2.4x the Haisco-announcement price, but a live drip facility caps near-term upside on a stock that has run 25% in two weeks on no new data.
- 2026-10-27 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - The Lottery Ticket Shows Its Numbers NXP200's ESMO oral confirmed the 40% glioma response rate with deep tumor shrinkage and clean tolerability, validating the paradox-breaker mechanism, though a ~7-month median DOR in high-grade glioma and no non-V600 data keep it the speculative leg.
- 2026-11-05 Speculative buy speculative UPDATE: Nuvectis Pharma (NVCT) - The ATM Found One Big Buyer, and the Canary Slipped Again The balance sheet is the strongest in company history with $140.7M cash and a second large healthcare-fund cheque at $23.36, but NXP900 slipped again to 1H 2027 and the ciprocopan U.S. path now hinges on an ambitious ask of FDA to accept Chinese-only data.
- Long call · opened Jun 24, 2026 at $24.48 · -14.6% vs XBI +1.7% (Nov 6, 2026)
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (1 quote from 1 filing)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“"We expect this funding to support our operations into the second half of 2029, providing a runway that extends well beyond multiple potential value-creating clinical and regulatory milestones.”
matched to NXP900 · readout other · read as second half of 2029
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Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (25)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from Jul 23, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Nov 4, 2026ReleaseNuvectis Pharma Reports Third Quarter 2026 Financial Results and Business Highlightsvia aggregator→ BD updateSummary on the 8-K
- Nov 4, 20268-KCurrent report: results of operations · EX-99.1 EXHIBIT 99.1→ BD updateThe Q3 report brings the first confirmation that FDA discussions on a U.S. ciprocopan path are "well underway," but the NXP900 Phase 1b combination update has quietly slipped to 1H 2027 — and the ATM's $37M single-fund placement finally starts to answer the institutional-sponsorship question.
- Nov 4, 202610-QQuarterly report→ BD updateSummary on the 8-K
- Nov 2, 2026ReleaseNuvectis Pharma to Report Third Quarter 2026 Financial Results on November 4, 2026via aggregator
- Oct 26, 2026ReleaseNuvectis Reports Positive Data from NXP200 Phase 1b Study Demonstrating Durable Responses, Including Complete Responses, in BRAF V600-mutated Recurrent or Progressive Gliomasvia aggregator→ BD updateThe ESMO oral I promised readers would be "the first dataset in this portfolio I can inspect rather than accept secondhand" just landed — and NXP200 delivered ~40% ORR with CRs in recurrent glioma, a 17-month median OS in high-grade patients, and responses in prior BRAF-inhibitor failures. The stock is down nearly 8% anyway.BD extracted 1 program update from this document → NVCT pipeline
- Oct 9, 2026ReleaseNuvectis Pharma to Participate in the Maxim Growth Summit 2026via aggregator
- Sep 24, 2026ReleaseNuvectis Announces NXP200 Granted Breakthrough Therapy Designation in China for BRAF V600-Mutant, Recurrent or Progressive, High-Grade Gliomavia aggregatorNXP200, the paradox-breaker BRAF inhibitor I've been calling the speculative leg of the Nuvectis portfolio, just received Breakthrough Therapy Designation in China for BRAF V600-mutant high-grade glioma — weeks before the ESMO oral that will show the dataset behind it for the first time.
- Sep 3, 2026ReleaseNuvectis Pharma To Participate in Upcoming Investor Conferencesvia aggregator
- Aug 21, 2026S-3Shelf registration→ BD update
- Aug 21, 20268-KCurrent report: other events→ BD update
- Aug 4, 2026ReleaseNuvectis Pharma Reports Second Quarter 2026 Financial Results and Business Highlightsvia aggregatorBD extracted 1 program update from this document → NVCT pipeline
- Aug 4, 20268-KCurrent report: results of operations · EX-99.1 EXHIBIT 99.1
- Aug 4, 202610-QQuarterly reportBD extracted 1 program update from this document → NVCT pipeline
- Jul 23, 2026ReleaseCorrection: (Title Correction) Nuvectis Announces Marketing Approval of Ciprocopan (NXP100) in China for the Treatment of Patients with PNH Previously Untreated with Complement Inhibitorsvia aggregator
- Jul 23, 2026ReleaseCiprocopan (NXP100) Receives Marketing Approval in China for the Treatment of Patients with PNH Previously Untreated with Complement Inhibitorsvia aggregator
- Jun 30, 20268-KCurrent report: material agreement, other events · EX-99.1 EXHIBIT 99.1
- Jun 30, 2026424B5Prospectus supplement (offering)
- Jun 29, 20268-KCurrent report: other events
- Jun 29, 2026424B5Prospectus supplement (offering)
- Jun 23, 20268-KCurrent report: material agreement, other events · EX-99.1 EXHIBIT 99.1
- Jun 12, 20268-KCurrent report: shareholder vote
- May 5, 20268-KCurrent report: results of operations · EX-99.1 EXHIBIT 99.1
- May 5, 202610-QQuarterly report
- Apr 27, 2026DEFA14AProxy soliciting material
- Apr 27, 2026DEF 14AProxy statement
2 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Aug 28, 2026EFFECTRegistration effective
- Aug 6, 2026SCHEDULE 13GPassive >5% holder (13G)