Jade Biosciences
Market cap $958M 63.6M shares (10-Q, Aug 3, 2026) × $15.07 close Nov 6, 2026
Most recent annual filing: 2026-03-06
- Parade warrant corporate updateDec 31, 2026Parade warrant corporate update, Dec 31, 2026, routine
- JADE201 Ph1 interim2027JADE201 Ph1 interim, 2027, material
- JADE301 HV Ph1 interim2H 2027JADE301 HV Ph1 interim, 2H 2027, material
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (4 active programs)
Capital (as filed)
- Cash
- $107M cash and cash equivalents · Jun 30, 2026 (10-Q)
- Short-term investments
- $354M Jun 30, 2026
- Operating cash flow
- −$43.7M quarter Mar 31, 2026 → Jun 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $461M cash, runway Q4 2028 per the update of Oct 21, 2026 — the company's own words as read there, not the filed figure
Offering documents (2)
- 2026-06-04 424B5 · Priced offering 10.0M shares · at $15.00 · $150M gross · 14.7% below the prior close ($17.59, Jun 3, 2026)
- 2026-05-15 424B3 · Resale (selling stockholders)
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (11)
- 2026-10-22 UPDATE: Jade Biosciences (JBIO) - EVERGREEN Arrives Early 🔒 Paid
- 2026-09-30 UPDATE: Jade Biosciences (JBIO) - The Wildcard’s Monkey Data, and a Stock Below the Deal Price 🔒 Paid
- 2026-08-11 UPDATE: Jade Biosciences (JBIO) - The Wildcard Has a Name: Interferon-Beta 🔒 Paid
- 2026-07-01 UPDATE: Jade Biosciences (JBIO) - The Wildcard Option Got Exercised 🔒 Paid
- 2026-06-04 UPDATE: Jade Biosciences (JBIO) - The Deal Priced at the Floor of My Range
- 2026-06-03 UPDATE: Jade Biosciences (JBIO) - The Dilution I Telegraphed, Just Not Through the Door I Expected
- 2026-06-02 UPDATE: Jade Biosciences (JBIO) - The Monkey Translated. The Stock Dropped 11.6% Anyway. 🔒 Paid
- 2026-05-29 UPDATE: Jade Biosciences (JBIO) - The Binary Has a Date: Monday, 8:00 a.m. ET 🔒 Paid
- 2026-05-27 UPDATE: Jade Biosciences (JBIO) - Two First-Patient-Dosed PRs Before the Monkey-to-Human Verdict 🔒 Paid
- 2026-05-08 UPDATE: Jade Biosciences (JBIO) - The $200M ATM Lands 6 Weeks Before the Monkey-to-Human Verdict 🔒 Paid
- 2026-05-06 Jade Biosciences (JBIO) - Scientific Deep Dive for JADE101 and Pipeline Products 🔒 Paid
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (11 calls)
Every verdict Biotech Distilled has published on Jade Biosciences, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-05-06 Watch Jade Biosciences (JBIO) - Scientific Deep Dive for JADE101 and Pipeline Products Jade's entire valuation rests on unproven monkey-to-human translation; wait for Q2 2026 Phase 1 human PK/PD data before taking a position.
- 2026-05-08 Watch UPDATE: Jade Biosciences (JBIO) - The $200M ATM Lands 6 Weeks Before the Monkey-to-Human Verdict The $200M ATM adds dilution overhang to the post-readout bull case but does not change the binary; continue waiting for Q2 human PK/PD data before entering.
- 2026-05-27 Watch UPDATE: Jade Biosciences (JBIO) - Two First-Patient-Dosed PRs Before the Monkey-to-Human Verdict Pre-readout Phase 2 enrollment amplifies the bear case on a miss but does not change the binary; maintain watch posture until Q2 HV data prints.
- 2026-05-29 Watch UPDATE: Jade Biosciences (JBIO) - The Binary Has a Date: Monday, 8:00 a.m. ET With the readout three trading days away, maintain watch posture; positions entered before Monday are a pure binary gamble on monkey-to-human translation.
- 2026-06-02 Speculative buy speculative UPDATE: Jade Biosciences (JBIO) - The Monkey Translated. The Stock Dropped 11.6% Anyway. All four binary risks (translation failure, PK collapse, ADAs, safety signal) were retired by the clean Phase 1 readout; the 11.6% drop is mechanical ATM overhang, not fundamental, making the $15–18 zone asymmetric entry.
- 2026-06-03 Speculative buy speculative UPDATE: Jade Biosciences (JBIO) - The Dilution I Telegraphed, Just Not Through the Door I Expected The marketed underwritten deal concentrates dilution into a single event rather than an ATM drip, and the likely $15–17 clearing range puts post-deal entry in the asymmetric zone with retired clinical risks.
- 2026-06-04 Speculative buy speculative UPDATE: Jade Biosciences (JBIO) - The Deal Priced at the Floor of My Range The 14.7% discount deal cleared at the floor of the asymmetric entry zone; clinical risks remain retired and ~$4.70/share cash post-raise supports the risk/reward at $15–17.
- 2026-07-01 Speculative buy speculative UPDATE: Jade Biosciences (JBIO) - The Wildcard Option Got Exercised JADE301 license formalizes a third Paragon asset on identical economics; the stock has rallied 23% off the deal floor but the ATM lockup expiry on ~July 3 is the near-term technical risk to watch.
- 2026-08-11 Speculative buy speculative UPDATE: Jade Biosciences (JBIO) - The Wildcard Has a Name: Interferon-Beta JADE301 named as anti-IFN-β for dermatomyositis with Q4 2026 Phase 1 pulled forward; $461M cash and runway into Q4 2028 fortify the balance sheet, though margin of safety is thinner at $21.73 than in early June.
- 2026-09-30 Speculative buy speculative UPDATE: Jade Biosciences (JBIO) - The Wildcard's Monkey Data, and a Stock Below the Deal Price JADE301 monkey data is competent and on-template, but the stock breaking below the $15 deal price creates overhead supply and makes the ATM a costlier tool; science is unchanged but waiting for Q3 10-Q to check ATM activity before sizing up is prudent.
- 2026-10-22 Speculative buy speculative UPDATE: Jade Biosciences (JBIO) - EVERGREEN Arrives Early EVERGREEN Phase 3 pulled to Q4 2026 defuses one of the two stated AVOID triggers; science unchanged and stock back above deal price, but Q3 10-Q ATM check still warranted before adding.
- Long call · opened Jun 2, 2026 at $17.75 · -15.1% vs XBI +19.1% (Nov 6, 2026)
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (3 quotes from 2 filings)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“We plan to initiate a registrational Phase 3 clinical trial in the first half of 2027, pending feedback and requirements from the U.S. Food and Drug Administration.”
matched to JADE101 · interim data · read as first half of 2027 -
“Phase 1 Trial in Healthy Volunteers We plan to initiate a Phase 1 trial of JADE301 in healthy volunteers in the fourth quarter of 2026.”
matched to JADE201 · interim data · read as fourth quarter of 2026
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“Phase 1 Trial in Healthy Volunteers We plan to initiate a Phase 1 trial of JADE301 in healthy volunteers in the fourth quarter of 2026.”
matched to JADE201 · interim data · read as fourth quarter of 2026
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Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (41)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from May 26, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Nov 3, 2026ReleaseJade Biosciences to Participate in Upcoming Conferences
- Oct 21, 2026ReleaseOCTOBER 21, 2026 Jade Biosciences to Highlight Advancement of JADE101 Development Program at American Society of Nephrology (ASN) Kidney Week 2026→ BD updateEVERGREEN, the JADE101 registrational Phase 3, just got pulled forward to Q4 2026 — a full quarter ahead of schedule — while the stock still sits within striking distance of the June deal-price floor.
- Sep 30, 2026ReleaseSEPTEMBER 30, 2026 Jade Biosciences Announces Preclinical Data Characterizing JADE301, a Potentially Best-in-Class, Half-Life-Extended Anti-IFN-B Monoclonal Antibody in Development for Dermatomyositis→ BD updateSummary on the 8-K
- Sep 30, 20268-KCurrent report: other events→ BD updateJADE301's EADV preclinical data landed this morning with a 25-day NHP half-life, ~73-75% predicted human SC bioavailability, and 8x potency over the dazukibart comparator — but the stock is at $14.05, down 35% from the August close, and the reaction needs decoding.
- Sep 1, 2026ReleaseSEPTEMBER 1, 2026 Jade Biosciences to Participate in Upcoming Conferences
- Aug 10, 2026ReleaseAUGUST 10, 2026 Jade Biosciences Reports Second Quarter 2026 Financial Results and Provides Corporate Update
- Aug 10, 20268-KCurrent report: results of operations · EX-99.1BD extracted 2 program updates from this document → JBIO pipeline
- Aug 10, 202610-QQuarterly report
- Jul 1, 20268-KCurrent report: material agreement
- Jun 26, 2026ReleaseJUNE 26, 2026 Jade Biosciences Announces Appointment of Mark Eisner, M.D., M.P.H., to Board of Directors
- Jun 26, 20268-KCurrent report: officer / director change, Reg FD disclosure · EX-99.1
- Jun 11, 20268-KCurrent report: charter / bylaws / fiscal year, shareholder vote
- Jun 9, 2026SCHEDULE 13D/A13D amendment
- Jun 5, 2026ReleaseJUNE 5, 2026 Jade Biosciences Announces Closing of Public Offering of Common Stock, Including Full Exercise of Underwriters Option to Purchase Additional Shares
- Jun 5, 2026DEFA14AProxy soliciting material
- Jun 4, 2026ReleaseJUNE 4, 2026 Jade Biosciences Announces Pricing of Public Offering of Common Stock
- Jun 4, 20268-KCurrent report: other events · EX-99.1
- Jun 4, 2026424B5Prospectus supplement (offering)
- Jun 3, 2026ReleaseJUNE 3, 2026 Jade Biosciences Announces Proposed Underwritten Public Offering
- Jun 3, 2026424B5Prospectus supplement (offering)
- Jun 1, 2026ReleaseJUNE 1, 2026 Jade Biosciences Announces Positive Interim Phase 1 Results for JADE101 Demonstrating Potential Best-in-Class Profile and Every-12-Week Dosing in IgA Nephropathy
- Jun 1, 20268-KCurrent report: Reg FD disclosure, other events · EX-99.1BD extracted 2 program updates from this document → JBIO pipeline
- May 29, 2026ReleaseMAY 29, 2026 Jade Biosciences to Host Conference Call and Webcast on June 1, 2026, at 8:00 a.m. ET to Discuss Interim Phase 1 Healthy Volunteer Results for JADE101, a Novel, Potentially Best-in-Class
- May 26, 2026ReleaseMAY 26, 2026 Jade Biosciences Announces First Participant Dosed in Phase 2 JUNIPER Clinical Trial of JADE101 in IgA Nephropathy
- May 26, 2026ReleaseMAY 26, 2026 Jade Biosciences Announces First Participant Dosed in First-in-Human Phase 1 Clinical Trial of JADE201, a Novel Half-Life Extended Afucosylated Anti-BAFF Receptor Monoclonal Antibody
- May 15, 2026424B3Prospectus (resale / update)
- May 7, 2026S-3Shelf registration
- May 7, 2026S-3Shelf registration
- May 7, 20268-KCurrent report: results of operations · EX-99.1
- May 7, 2026424B3Prospectus (resale / update)
- May 7, 2026424B3Prospectus (resale / update)
- May 7, 202610-QQuarterly report
- Apr 28, 2026DEFA14AProxy soliciting material
- Apr 28, 2026DEF 14AProxy statement
- Apr 22, 20268-KCurrent report: officer / director change
- Apr 2, 20268-KCurrent report: officer / director change
- Mar 6, 20268-KCurrent report: results of operations · EX-99.1
- Mar 6, 2026424B3Prospectus (resale / update)
- Mar 6, 2026424B3Prospectus (resale / update)
- Mar 6, 202610-KAnnual report
- Mar 5, 2026SCHEDULE 13D/A13D amendment
20 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Oct 28, 2026SCHEDULE 13GPassive >5% holder (13G)
- Oct 27, 2026SCHEDULE 13GPassive >5% holder (13G)
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Jul 17, 2026SCHEDULE 13GPassive >5% holder (13G)
- Jul 8, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026SCHEDULE 13G/A13G amendment
- May 15, 2026EFFECTRegistration effective
- May 15, 2026EFFECTRegistration effective
- May 13, 2026UPLOADUPLOAD
- May 13, 2026UPLOADUPLOAD
- May 13, 2026CORRESPCORRESP
- May 13, 2026CORRESPCORRESP
- May 7, 2026S-8Employee plan registration
- Apr 28, 2026ARSAnnual report to shareholders
- Apr 27, 2026SCHEDULE 13G/A13G amendment
- Apr 17, 2026PRE 14APRE 14A
- Mar 6, 2026S-8Employee plan registration
- Mar 6, 2026POS EXPOS EX
- Mar 6, 2026POS EXPOS EX