Connect Biopharma
Market cap $45.9M 63.0M shares (10-Q, Jul 31, 2026) × $0.729 close Nov 6, 2026
Most recent annual filing: 2026-03-31
- Rademikibart atopic dermatitis China decision2H 2026Rademikibart atopic dermatitis China decision, 2H 2026, material
- Rademikibart FDA feedback4Q 2026Rademikibart FDA feedback, 4Q 2026, notable
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (4 active programs)
Discontinued (1)
- rademikibart — Atopic Dermatitis · Connect has decided to not currently pursue further development of rademikibart for AD
Capital (as filed)
- Cash
- $27.0M cash and cash equivalents · Jun 30, 2026 (10-Q)
- Short-term investments
- $4.5M Jun 30, 2026
- Operating cash flow
- −$15.9M quarter Mar 31, 2026 → Jun 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $31.5M cash per the update of Sep 30, 2026 — the company's own words as read there, not the filed figure
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (4)
- 2026-09-30 UPDATE: Connect Biopharma (CNTB) - The Mirror Image 🔒 Paid
- 2026-09-16 UPDATE: Connect Biopharma (CNTB) - The Trial Failed. The Drug Might Not Have. 🔒 Paid
- 2026-08-13 UPDATE: Connect Biopharma (CNTB) - The Clock Is Set, The Cushion Is Gone 🔒 Paid
- 2026-06-08 Connect Biopharma (CNTB) - Scientific Deep Dive for Rademikibart and Pipeline Products
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (4 calls)
Every verdict Biotech Distilled has published on Connect Biopharma, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-06-08 Watch Connect Biopharma (CNTB) - Scientific Deep Dive for Rademikibart and Pipeline Products Differentiated mechanism and real acute-exacerbation white space, but the entire equity hinges on one funded-but-binary mid-2026 Seabreeze readout in a novel endpoint, against subgroup-heavy supporting data and a China-structure/Phase-3-dilution overhang.
- 2026-08-13 Speculative buy speculative UPDATE: Connect Biopharma (CNTB) - The Clock Is Set, The Cushion Is Gone Upgrade is narrow and calendar-driven: readout now has a month, both trials finished enrollment at plan with no sample-size expansion, and Simcere milestone cash is flowing — asymmetry intact with timing certainty, but sized only as a small event-sized starter given the thinned cash cushion.
- 2026-09-16 Watch UPDATE: Connect Biopharma (CNTB) - The Trial Failed. The Drug Might Not Have. Asthma trial missed its primary endpoint on only 8 events (p=0.153), forcing a raise from a broken tape without a re-rating; the mechanistic FEV1 secondary hit but the endpoint the equity was priced on failed, and the dilution event is now unavoidable before COPD data and FDA endpoint clarity.
- 2026-09-30 Watch UPDATE: Connect Biopharma (CNTB) - The Mirror Image COPD hit the clinical-outcome primary (81% fewer treatment failures, p=0.0122) but missed Day-7 FEV1, each trial won on a different endpoint, and the imminent dilutive raise keeps the stance at Watch until a fairly priced deal and constructive FDA read would justify a SPEC_BUY upgrade.
- Long call · opened Aug 13, 2026 at $2.54 · closed Sep 16, 2026 (downgraded to WATCH from long) at $1.24 · -51.2% vs XBI -1.7%
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (2 quotes from 2 filings)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“Topline data from both studies are expected in September 2026, which should help determine a potential Phase 3 endpoint and sample size requirements.”
matched to Rademikibart · regulatory submission · read as September 2026
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“Topline data from both studies are expected in September 2026, which should help determine a potential Phase 3 endpoint and sample size requirements. ◦ Following topline results, the Company plans to meet with the FDA to gain alignment on a Phase 3 program.”
matched to Rademikibart · regulatory submission · read as September 2026
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Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (16)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from Aug 12, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Sep 30, 2026ReleaseConnect Biopharma Announces Positive Preliminary Topline Data from its Global Phase 2 Study of Rademikibart as an Add-on Treatment for Acute Exacerbations in Adults with COPD and Type 2 Inflammation→ BD updateSummary on the 8-K
- Sep 30, 20268-KCurrent report: Reg FD disclosure, other events · EX-99.1→ BD updateSeabreeze STAT COPD hit — rademikibart cut treatment failure 81% (p=0.0122) and eliminated all hospital/ED returns — delivering the clean primary endpoint the asthma trial couldn't generate two weeks ago, while the key FEV₁ secondary missed and the financing clock keeps ticking.BD extracted 1 program update from this document → CNTB pipeline
- Sep 15, 2026ReleaseConnect Biopharma Announces Positive Preliminary Topline Data from its Global Phase 2 Study of Rademikibart as an Add-on Treatment for Acute Exacerbations in Adult and Adolescent Participants with Ast→ BD updateSummary on the 8-K
- Sep 15, 20268-KCurrent report: Reg FD disclosure, other events · EX-99.1→ BD updateThe Seabreeze STAT Asthma coin has landed — and it landed on its edge. Rademikibart's Day 7 FEV₁ signal hit (Δ130 mL, p=0.023), but the primary treatment-failure endpoint missed statistical significance (p=0.153), and the stock has cratered ~50% on data that the company is calling "positive."BD extracted 1 program update from this document → CNTB pipeline
- Sep 3, 2026ReleaseConnect Biopharma to Present at the H.C. Wainwright 28th Annual Global Investment Conference
- Aug 12, 2026ReleaseConnect Biopharma Reports Second Quarter 2026 Financial Results and Provides Business Update
- Aug 12, 20268-KCurrent report: results of operations · EX-99.1
- Aug 12, 202610-QQuarterly reportBD extracted 1 program update from this document → CNTB pipeline
- May 15, 2026F-3Shelf registration (foreign)
- May 12, 20268-KCurrent report: results of operations · EX-99.1
- May 12, 202610-QQuarterly report
- Apr 23, 20268-KCurrent report: Reg FD disclosure, other events · EX-99.1
- Apr 1, 2026SCHEDULE 13D/A13D amendment
- Mar 31, 20268-KCurrent report: results of operations · EX-99.1
- Mar 31, 202610-KAnnual report
- Mar 30, 20268-KCurrent report: material agreement, unregistered sale of equity, Reg FD disclosure · EX-99.1
9 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Nov 3, 2026SCHEDULE 13G/A13G amendment
- Oct 6, 2026SCHEDULE 13GPassive >5% holder (13G)
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Aug 14, 2026SCHEDULE 13G/A13G amendment
- Jun 1, 2026EFFECTRegistration effective
- May 28, 2026CORRESPCORRESP
- May 22, 2026UPLOADUPLOAD
- May 15, 2026SCHEDULE 13G/A13G amendment
- Apr 14, 2026SCHEDULE 13GPassive >5% holder (13G)