BridgeBio Oncology Therapeutics
Market cap $164M 80.2M shares (10-Q, Aug 6, 2026) × $2.04 close Nov 6, 2026
Most recent annual filing: 2026-03-15
- BBO-10203 readout2H 2026BBO-10203 readout, 2H 2026, major
- BBOT pipeline BBO-11818 Ph1 readout2H 2026BBOT pipeline BBO-11818 Ph1 readout, 2H 2026, major
- BBO-11818 Ph1 interim2H 2026BBO-11818 Ph1 interim, 2H 2026, material
Bar width shows how precise the guidance is — a pin is a stated date, a wide band a six-month window. Deeper blue means more of the thesis rides on the event; it is not a view on the stock.
Pipeline (6 active programs)
BBO-10203
Discontinued (2)
- BBO-8520 — Non-Small Cell Lung Cancer · strategic deprioritization due to evolving treatment landscape, competitive crowding, and portfolio dynamics
- BBO-10203 — Breast Cancer · strategic deprioritization due to evolving treatment landscape, competitive crowding, and portfolio dynamics
Capital (as filed)
- Cash
- $54.1M cash and cash equivalents · Jun 30, 2026 (10-Q)
- Short-term investments
- $172M Jun 30, 2026
- Long-term investments
- $118M Jun 30, 2026
- Operating cash flow
- −$44.4M quarter Mar 31, 2026 → Jun 30, 2026, year-to-date difference (10-Q)
- As stated in coverage
- $344M cash, runway into 2028 per the update of Sep 8, 2026 — the company's own words as read there, not the filed figure
Offering documents (4)
- 2026-09-01 S-3 · Shelf registration
- 2026-08-12 424B3 · Resale (selling stockholders)
- 2026-06-22 424B3 · Resale (selling stockholders)
- 2026-05-13 424B3 · Resale (selling stockholders)
Cash, investments and operating cash flow are the company's own XBRL facts as filed with the SEC, each shown with its period end and tag. As-stated figures come from the company's own words as read in Biotech Distilled coverage, dated, and routinely count securities and planned financing that a balance sheet does not. Offering rows are the SEC cover pages as filed. Not investment advice. Figures as of Nov 7, 2026.
Biotech Distilled coverage (5)
- 2026-09-08 UPDATE: BridgeBio Oncology (BBOT) - The n Finally Moved 🔒 Paid
- 2026-09-02 UPDATE: BridgeBio Oncology (BBOT) - The ATM Arrives Ninety Days Early 🔒 Paid
- 2026-08-12 UPDATE: BridgeBio Oncology (BBOT) - The Internal Combo Leaves the Lab 🔒 Paid
- 2026-04-27 UPDATE: BridgeBio Oncology (BBOT) - The CSO Takes the Wheel, the FDA Hands Out a Hall Pass 🔒 Paid
- 2026-04-20 BridgeBio Oncology (BBOT) - Scientific Deep Dive for BBO-8520, BBO-11818, and BBO-10203 🔒 Paid
Articles open on Substack. Some are subscriber-only; those marked ★ Distilled Pro are for Distilled Pro members.
Verdict history (5 calls)
Every verdict Biotech Distilled has published on BridgeBio Oncology Therapeutics, oldest first — the full history, never a selection. How calls are scored: the track record.
- 2026-04-20 Watch BridgeBio Oncology (BBOT) - Scientific Deep Dive for BBO-8520, BBO-11818, and BBO-10203 Elegant ON/OFF KRAS inhibition and RAS:PI3Kα breaker chemistry with a pristine balance sheet, but micro-cohort data warrants waiting for Phase 1b/2 expansion readouts in late 2026 before committing capital.
- 2026-04-27 Watch UPDATE: BridgeBio Oncology (BBOT) - The CSO Takes the Wheel, the FDA Hands Out a Hall Pass Fast Track designation for BBO-11818, BridgeBio founder taking executive control, and supportive AACR preclinical data modestly strengthen the thesis, but the clinical n remains too small to change the stance.
- 2026-08-12 Watch UPDATE: BridgeBio Oncology (BBOT) - The Internal Combo Leaves the Lab Internal KRAS+PI3Kα combinations are now dosing in patients and execution is on track, but the clinical dataset is unchanged and burn is accelerating, keeping the watch stance intact ahead of 2H 2026 readouts.
- 2026-09-02 Watch UPDATE: BridgeBio Oncology (BBOT) - The ATM Arrives Ninety Days Early A $200M ATM facility filed 90 days before binary readouts adds a dilution overhang without changing the science, keeping the watch stance but making the asymmetry slightly less clean for prospective buyers.
- 2026-09-08 Speculative buy speculative UPDATE: BridgeBio Oncology (BBOT) - The n Finally Moved BBO-8520 monotherapy ORR held at 63% as the cohort tripled to 41 patients with 100% DCR and no grade 3 liver elevations, materially de-risking the efficacy-erosion failure mode, though the commercial ceiling narrowed to 2L+ salvage and confirmatory data slipped to mid-2027 with a live $200M ATM in the gap.
- Long call · opened Sep 9, 2026 at $6.75 · -69.8% vs XBI -4.5% (Nov 6, 2026)
Every verdict Biotech Distilled has published on this company, in order, with the post it came from — the full history, never a selection. Position figures are the same ones shown on /track-record, computed by the same method. Editorial opinion, not investment advice.
Timing, in the company's words (6 quotes from 2 filings)
Sentences quoted verbatim from the company's SEC filings, newest filing first. Each sits under the filing it appeared in; the "matched to" tag names the calendar row it was read for.
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“Updated clinical data are expected in the second half of 2026.”
matched to BBO-10203 · readout other · read as second half of 2026 -
“Updated Phase 1 clinical data are expected in the second half of 2026.”
matched to BBO-11818 · interim data · read as second half of 2026 -
“Updated clinical data are expected in the second half of 2026 and an internal combination study with BBO-10203 opened in April 2026.”
matched to BBO-8520 · readout other · read as second half of 2026
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“Updated clinical data are expected in the second half of 2026.”
matched to BBO-10203 · readout other · read as second half of 2026 -
“Updated Phase 1 clinical data are expected in the second half of 2026.”
matched to BBO-11818 · interim data · read as second half of 2026 -
“Updated clinical data are expected in the second half of 2026 and an internal combination study with BBO-10203 opened in April 2026.”
matched to BBO-8520 · readout other · read as second half of 2026
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Timing sentences quoted from the company's own SEC filings, each under the filing it appeared in. The 'matched to' tag is the calendar row the sentence was read for; the filing is the source. Not investment advice.
Filings & releases (28)
SEC filings from EDGAR and press releases captured from the company's investor-relations site, newest first. Releases captured from May 12, 2026; filings from March 2026. Summaries come from the BD update that read the document; "BD extracted" counts point at the pipeline table above. All companies →
- Nov 5, 20268-KCurrent report: officer / director change
- Sep 8, 2026ReleaseBBOT Announces New BBO-8520 Data; Highlights Strategic Focus on 2L+ NSCLC BBO-8520 Combination as Well as BBO-11818 and BBO-10203 Combinations in KRAS-Mutant Cancers→ BD updateSummary on the 8-KBD extracted 2 program updates from this document → BBOT pipeline
- Sep 8, 20268-KCurrent report: other events · EX-99.1→ BD updateThe 2H 2026 data has arrived: BBO-8520 monotherapy holds its ORR at scale (63%, n=41) with a 100% disease control rate and zero Grade 3 liver events, while the pembrolizumab combo in inhibitor-experienced NSCLC hits 75% ORR at the lead dose — and BBOT just declared its strategic endgame.BD extracted 5 program updates from this document → BBOT pipeline
- Sep 1, 2026S-3Shelf registration→ BD updateBBOT quietly filed a $500M shelf and activated a $200M ATM facility on the same day it registered 63M legacy shares for resale — materially changing the dilution picture heading into the 2H 2026 data catalysts.
- Sep 1, 2026ReleaseBBOT to Participate in Upcoming Investor Healthcare Conferences→ BD updateSummary on the S-3
- Aug 12, 2026424B3Prospectus (resale / update)
- Aug 11, 2026ReleaseBBOT Reports Second Quarter 2026 Financial Results and Update on Corporate Progress
- Aug 11, 20268-KCurrent report: results of operations · EX-99.1
- Aug 11, 202610-QQuarterly report
- Jul 6, 2026SCHEDULE 13D/A13D amendment
- Jun 22, 20268-KCurrent report: officer / director change, shareholder vote
- Jun 22, 2026424B3Prospectus (resale / update)
- May 13, 2026424B3Prospectus (resale / update)
- May 12, 2026ReleaseBBOT Reports First Quarter 2026 Financial Results and Update on Corporate Progress
- May 12, 20268-KCurrent report: results of operations · EX-99.1
- May 12, 202610-QQuarterly report
- May 6, 2026424B3Prospectus (resale / update)
- Apr 29, 20268-KCurrent report: officer / director change
- Apr 29, 2026424B3Prospectus (resale / update)
- Apr 28, 2026DEFA14AProxy soliciting material
- Apr 28, 2026DEF 14AProxy statement
- Apr 23, 20268-KCurrent report: officer / director change, Reg FD disclosure · EX-99.1
- Apr 23, 2026424B3Prospectus (resale / update)
- Mar 26, 20268-KCurrent report: officer / director change
- Mar 26, 2026424B3Prospectus (resale / update)
- Mar 6, 2026424B3Prospectus (resale / update)
- Mar 5, 20268-KCurrent report: results of operations · EX-99.1
- Mar 5, 202610-KAnnual report
6 more filings (13G holder notices, S-8, proxy material, SEC correspondence …)
- Sep 10, 2026EFFECTRegistration effective
- Sep 8, 2026EFFECTRegistration effective→ BD updateSummary on the 8-K
- Sep 1, 2026POS AMPost-effective amendment→ BD updateSummary on the S-3
- May 4, 2026EFFECTRegistration effective
- Apr 30, 2026POS AMPost-effective amendment
- Apr 28, 2026ARSAnnual report to shareholders